在这部在下坂本，有何贵干？喜剧/动画片中,县立学文高中一年级2班，那里有位刚一入学就得到全校注目的男子，他的名字叫坂本（绿川光 配音）。他戴着黑边框眼镜，个人特征是左眼下的泪痣。他不但相貌英俊，着装整齐，而且眼神凌厉，一举一动都华丽潇洒，帅气爆表，因此总能成为众人的焦点，受到女生们的疯狂追捧，但是也因此引起不少同龄男生的嫉妒，包括同班同学阿酱（杉田智和 配音），以及高二级学长8823（游佐浩二 配音）。对面男生们花样百出的陷害和报复，坂本总能帅气满分地完美解决这些麻烦，让男生们甘拜下风。
本剧改编自日本漫画家佐野菜见原作的同名漫画。
First year high school student Sakamoto isn't just cool, he's the coolest! Almost immediately after starting school, he began attracting everyone's attention. The girls love him, and most of the boys resent him. There's even a boy in the class who works as a model, but who is constantly upstaged by Sakamoto! No matter what tricks the other boys try to play on him, Sakamoto always manages to foil them with ease and grace. Though Sakamoto may seem cool and aloof, he helps others when asked, such as in the case of the boy in his class who was being constantly bullied. No matter what difficulties Sakamoto encounters, he moves through his high school life with confidence and class.
这个故事真的非常SAD。他叫坂本他有毒。将不可能动画化的作品做成动画——监督高松信司谈《在下坂本》。装b搞笑是看点，但这个故事真的非常有境界。Mr.Coolest大解剖——中岛敦子谈《在下坂本》人设。在下坂本，有何贵干：后退，我要开始装逼了。有趣的人设。坂本君，听说你是4月最正经搞笑？。可怜你帅不赢坂本大佬。。坂本是最帅的人生导师。
