在这部魔法老师喜剧/爱情/动画/奇幻片中,虽然涅吉（佐藤利奈 配音）只有10岁，但他强大的魔法能力使得他足以担负起任教麻帆良学院的重任，只是，性格有些害羞又未经人事的涅吉，要他面对班上31名年长且清纯可爱的女生，这样真的没问题吗？
每一个魔法使的身边，都会存在一个保护大的勇士，两人之间要签订契约，生死与共。而一直没有勇士相伴的涅吉，居然在阴差阳错之下，和自己的学生，巨力系少女神乐坂明日菜（神田朱未 配音）签订了契约。除此之外，情报通朝仓和美（笹川亚矢奈 配音），文学少女绫濑夕映（桑谷夏子 配音），阴阳师近卫木乃香（近卫木乃香 配音），这些女孩子们的出现，也为涅吉惊险刺激的生活增添了一份欢乐。
Negi Springfield is only 10 years old, but he is trying to become a wizard(Magister Magi) but he was sent to Japan for training, despite the protests from his sister. The principal, who was a friend of his grandfather, assigned him to be the homeroom teacher and English instructor of middle school which is an all girls school. And the class is full of girls, with "special" characteristics, like one being a vampire, another a ghost, another a robot, and others being athletes and bookworms. Negi puts a lot of good will towards everyone and works hard to teach them, and even though most of the girls are very friendly with him, they see him more as a kid to have fun with instead of a respectful instructor, except a few of them, that hate the concept of him being a teacher, one of them is an anti-social computer nerd and the other is a hard worker who had a crush on the previous teacher, and to make matters worse, she found out about Negi, and his magic. Think of it as a Harry Potter meets Love Hina meets Azumanga Daioh meets Sensei no Ojikan Doki Doki School Hours, except picture it in a middle school.
