在这部疯子2剧情/喜剧/恐怖片中,精神错乱、吸毒成瘾、有厌女症的疯子哈里·鲁索痛苦地回忆起他小时候父母虐待他的经历。在他的腹语表演者假朋友拉布尼克的陪同下，鲁索在拉斯维加斯开始了一场残酷的精神病狂欢，在那场狂欢中他强奸和谋杀了老太太、女同性恋搭车者和肮脏的两个小妓女。与此同时，两个卑鄙的警察试图抓获鲁索。
Deranged and drug-addled misogynistic lunatic Harry Russo suffers from painful flashbacks concerning the abuse he suffered from his parents as a kid. Accompanied by his ventriloquist dummy pal Rubberneck, Russo embarks on a brutal psychotic spree in Las Vegas in which he rapes and murders old ladies, lesbian hitchhikers, and sleazy two-bit whores. Meanwhile, two scummy cops try to nab Russo.
