在这部机械战警：终极毁灭动作/科幻/犯罪片中,墨菲在一次追捕犯人的任务中惨遭杀害，经过科学精密的改装后，他成了无坚不摧的机器战警，警方以他来打击地方上的罪恶无往不利，却没想到竟操纵在利益团体手中，而因为他仍存有以前的记忆，为了复仇，为了铲奸除恶，决定大干一场。
Thirteen years after the original Robocop, Delta City, considered to be "The Safest Place On Earth!", has become a futuristic city owned and operated by OCP, and RoboCop, Alex Murphy has begun to feel his age. Murphy finds himself nearly obsolete, and must deal with the fact that his now-grown son James is an OCP executive, unaware that his father is still alive. Also, Murphy's former partner, John Cable, has returned to Delta City as its new Security Commander. But slowly, new enemies arise, and Murphy and Cable begin an investigation into a mysterious villain known as the Bone Machine, unaware that they are coming dangerously close to exposing an evil group of OCP executives known as The Trust... which James Murphy is a part of. Desperate to prevent their sinister plans from being revealed, The Trust programs Murphy to kill John Cable...
