在这部结晶艳舞科幻/恐怖片中,校队篮球运动员马特（Brian Lloyd 饰）等人经历了一场暴力的校际篮球比赛，对方粗野的主场把马特与队友乔伊、布莱恩送进了当地医院。乔伊小妹切丽暗恋马特，无奈马特的拉拉队长女友不给机会。另一方面，这所医院收治的一名女性病人被外星生物寄生，寄生生物通过控制宿主陆续感染控制了护士、医生以及病人。女性感染后被充作寄生生物的诱饵，而男性则化为无自我意识的养料。
马特等人发现了医院的异样，但为时已晚，感染者在医院中横行，乔伊也因受伤开始转化。走投无路的年轻人们决意对抗外星生物，他们摧毁了地下室中的外星培养缸，切丽更发现了这种嗜甜生物的致命弱点……
In a lonely road in Wucaipa, something attacks the driver of a car and her blind friend Tammy. They have a car accident; Tammy survives and is sent to the Wucaipa General Hospital. Meanwhile, a high school basketball team fights with the opponents in the square and the captain Matt with a broken leg, and his injured friends Joey and Brian are sent to the same hospital. Tammy is near death and asks the candy striper nurse Janine to kiss her. While kissing as a gesture of sympathy, an alien invades the mouth of Janine and infects her; she infects others nurses, clerks, doctors and patients, initiating an exponential virus outbreak in the hospital. Joey's sister Cherie that has a crush on Matt stays with them in the hospital. When Joey is infected by a hot nurse during the night, he has webbing on the face and rush, and Matt asks Cherie to call his girlfriend Krystal to help them to leave the hospital. But the place is under quarantine and the candy stripers need sugar to procreate a ...
