在这部佳人有约动作/冒险片中,女医生蕾切尔惊闻三年未见的哥哥大卫在约旦过世，于是作为唯一亲属跟随美国国务院官员杰克前往约旦确认遗体。当她到达约旦却发现身为考古爱好者的大卫的死亡极为蹊跷，并且仿佛与失落的古文明“死海古卷”有关。蕾切尔决意调查事情的真相。杰克一方面为了保护蕾切尔的安全，一方面受命上级的要求，遂与蕾切尔一同追查“死海古卷”的下落。二人远赴迪拜，见到大卫生前最后试图联系的古董收藏家，获悉线索后又重回约旦追查。然而，想要得到古卷的还有一伙极端分子。蕾切尔与杰克经历追杀、绑架，甚至险些迷失在沙漠中，终于逃出生天。惊魂甫定，蕾切尔灵光一现，领悟到大卫想要传达给自己的信息，并顺利得到古卷，却没想到再次落入极端分子的圈套。蕾切尔与杰克冒着生命危险，制服恶徒，保护古卷，最终按照大卫的遗愿将古卷在博物馆展出，以供考古研究。他们二人也在经历生死后对彼此产生依恋。
RACHEL, a Jewish-American doctor, and JAKE, an Arab-American government bureaucrat, go on a goose chase across the Middle East trying to solve the mysterious death of Rachel's treasure hunting brother. From Los Angeles to the deserts of Jordan and the ancient city of Petra, they find themselves hunted by a doomsday group called the Armageddonites who believe Rachel and Jake possess the missing Dead Sea Scroll that could bring about the end of days. Caught in the middle of a plot to hasten the end of mankind, Rachel and Jake need to solve the murder, find the scroll and find trust in each other.
