在这部逃亡快车动作片中,海关缉私队长布鲁克里在一次缉私行动中缴获了以西敏诺夫为首的俄罗斯恐怖分子走私的沙林毒气，这起事件引起了FBI和俄方的注意，美国军方遂要求将毒气秘密运顺华府，不料半路西敏诺夫逃递并劫持运送毒气的列车。当正义与邪恶在车上为争抢毒气而大开杀戒时。最后他们发现毒气不在车上，此时美国军战机决定制造雪崩将列车埋没，面对雪崩和夺命飞车，布鲁克斯不得不做出生死抉择……
Agent Brooks tells his side of a botched job at a job interview for for the Head of Customs in Alaska. He takes a tip that a shipment of bio-weaponry is coming in and discovers a Russian terrorist, Simeonov, is behind it. Brooks assembles a team and they go down to the docks to check the tip out. There a shoot-fest follows, an undercover FBI agent surfaces and a Russian agent, Natalya arrives to claim rights over Simeonov. Simeonov is arrested but while being transferred to Washington he escapes and with his fellow terrorists hijack the train carrying the stolen Russian nerve gas.
